CSE: BUX | OTCQB: BMKDF | FSE: 20B

About BioMark Diagnostics

BioMark is committed to pushing the limits of detection to deliver complementary diagnostic solutions across the entire cancer care pathway.

What Drives Us?

Female scientist in a white lab coat seated at a laboratory mass spectrometer in BioMark's Diagnostics facility, analyzing samples for metabolomics-based liquid biopsy cancer testing.

What drives us is simple: research that ends in a decision. We invest in science rigorous enough to publish and specific enough for a clinician to act on.

Science Powering BioMark

Portrait concept illustration of BioMark’s metabolomics-to-AI workflow: a dense cloud of metabolite molecules and chromatogram traces flows into a neural network and resolves into a simple clinical score ring and a clean report card.

BioMark combines evidence-based metabolomic science with AI/ML to transform complex cancer-associated metabolic patterns into a clinically interpretable score and actionable report.

Who We Are

Oncology Focused

BioMark is an oncology-focused company developing advanced, near-to-market liquid biopsy diagnostic technologies. Our approach is designed to make cancer screening more comfortable for patients, support better outcomes, and enable earlier detection, when treatment is most effective.

BioMark holds a portfolio of intellectual property for the detection and quantitation of metabolites, forming the foundation of our diagnostic platform.

Our global team brings together hand-picked scientists, engineers, and medical professionals with proven track records. United by a shared goal, we are working to bring our innovative technology to market and to improve the predictive accuracy of early-stage cancer detection. In everything we do, we hold ourselves to the highest regulatory, clinical, and scientific standards.

Since our founding in 2007, our mission has remained unchanged: to develop and commercialize innovative technologies that improve the accuracy and prediction of early-stage cancer diagnosis.

Empowering People

Cancer care shouldn’t depend on where you live or which clinic you can reach. While we work closely with physicians and medical institutions, our goal reaches further: to empower individuals and nations with universal access to effective cancer diagnostic tools.

At BioMark, we are working to make effective cancer management solutions faster and more widely available, because earlier answers can mean better outcomes for patients everywhere.

empowering oncologists and physicians with early stage cancer detection tools

Committed to the Highest Standards of Validation

Biomarkers are central to every stage of cancer care, from early detection and diagnosis to treatment monitoring and survivorship. That is why BioMark applies the highest levels of scientific and clinical rigor to every aspect of our development process.

Through meticulous analytical validation, robust clinical validation, and thorough assessment of clinical utility, we ensure our metabolite-based technologies meet the stringent requirements for safe, reliable integration into routine patient care.

This uncompromising commitment to excellence is embedded in BioMark’s daily operations and drives everything we do.

BioMark's Mission

To make cancer risk measurable at the first point of care, giving clinicians the clarity to know who needs further investigation and how to act on what they find.

Executive Team & Advisors

Cross-pollinated expertise driving innovation since 2007.

Executive Team and Advisors

Core executives include Founder & CEO Rashid Ahmed Bux (MBA), CSO Dr. Jean-François (PhD), CFO Gina Huang, and CTO Brian Cheng. Advisors include Dr. David Wishart, Dr. Christian Rolfo, Dr. Myron Weisfeldt, and strategic leaders including Alfred Berkeley and James Lavender.
More Information

Awards, Grants, Recognitions

Validated excellence in cancer research and innovation.

Awards, Grants, and Recognition

BioMark has received funding and honors from NRC IRAP, Genome BC, Mitacs, Research Manitoba, and NSERC Engage. Highlights include the ADRIQ Innovation Award, IUCPQ-UL, AstraZeneca Canada, Pfizer Canada, Spark Grants, TMIC, and the Canadian Technology Accelerator.
More Information

Careers

Career opportunities with BioMark Diagnostics.

Careers

At BioMark, data and AI scientists, cancer researchers, and assay specialists work side by side to decode cancer-associated metabolic patterns, build interpretable models, and ship liquid-biopsy scores and reports that support earlier detection and better decisions.
More Information

Strategic Collaborations

Partnerships with global leaders in research and industry.

Strategic Collaborations

BioMark's collaborations with premier institutions and industry partners include AstraZeneca, Pfizer Canada, SCIEX, Phytronix, IUCPQ-Université Laval, The James Cancer Center – the Ohio State University, University of Maryland, Johns Hopkins, University of Manitoba, University of Alberta, and participations in trials like HANSE.
More Information

The BioMark Team

"A leadership team of scientists, physicians, engineers, and business leaders with decades of diagnostic expertise that drives discovery, reduces risks, and accelerates clinical adoption with biopharma partners."

Leadership

rashid a

Rashid A. Bux

Founder, CEO, & Director

  • Co-founder and COO, Optima Health and KKT Spinecentres
  • Founder and President, Homeworks
  • MBA, University of Western Ontario
  • B.Sc. Business Administration, Miami University (Magna Cum Laude)
guoyu gina huang

Guoyu (Gina) Huang

Chief Financial Officer

  • Founded a financial consulting firm
  • MBA, Vancouver Island University
  • M.S., University of Hertfordshire
Jean Francois Haince

Dr. Jean-Francois Haince

Chief Scientific Officer

  • 15+ years in cancer research; 20+ peer-reviewed publications
  • Led molecular diagnostic test development at DiagnoCure
  • Ph.D. Cellular and Molecular Biology, Université Laval

Board of Directors

Brian Cheng

Brian Kai-Ming Cheng

Director

  • 31+ years in technology development and commercialization at Monsanto, Covidien and Sensient Pharmaceutical Group
  • 35+ patents in drug development, manufacturing process and formulation
bramhanand ramjiawan

Dr. Bramhanand Ramjiawan

Director

  • Director of Research Innovation and Regulatory Affairs, Asper Clinical Research Institute, St. Boniface Hospital
  • Adjunct Professor of Pharmacology and Therapeutics, University of Manitoba
  • Reviewer for U.S. NIH and the EU Commission on Health Science and Ethics
James A. Lavender

James A. Lavender

Director

  • 30+ years experience in data modeling, management and analysis focused on application development in both government and civilian sectors.
  • B.S. Computer Science, United States Naval Academy.

Strategic and Scientific Advisors

Strategic Advisors

Al Berkeley
Mr. Alfred R. Berkeley

Strategic and Financial Advisor. Former President of Nasdaq

all headshots with sides punched out
Vice Admiral Kevin Cosgriff

Innovation and Investment Strategy

Randolph Ford
Dr. Randolph Ford

AI and ML Strategic Advisor

Theresa Peterson
Theresa Peterson

Government Liaison and Community Engagement

Clinical and Scientific Advisors

David Wishart
Dr. David Wishart

Professor, Computing Science and Biological Sciences, University of Alberta

Christian Rolfo
Dr. Christian Rolfo

M.D., The Ohio State University, Director of the Division of Medical Oncology at OSUCCC-James

Myron L. Weisfeldt
Dr. Myron L. Weisfeldt

M.D., University Service Professor of Medicine, The Johns Hopkins Hospital

Donald Miller
Dr. Donald Miller

Professor, Pharmacology and Therapeutics, University of Manitoba

Maria Vaida
Dr. Maria Vaida

Assistant Professor of Data Science, Harrisburg University

Auditor

MNP LLP

Accounting, Business Consulting, and Tax Services

Legal Counsel

Legal Counsel – Corporate: Cozen O’Connor

Legal Counsel – Patent: ROBIC LLP

Transfer Agent

Endeavor Trust Corporation

Grants, Recognitions, Research Awards

BioMark’s innovative metabolomics and AI platform is earning broad acclaim from top academic institutions, government bodies, and industry leaders, underscoring its promise to revolutionize early cancer detection.

Major Funding

Academic Collaborations

Timeline of Funding and Grants

2026/2027

NRC Horizon Europe Funding: Secured to support European expansion and collaborative research.

2025 Financing Separate from Grants

Raised a total of approximately CAD $4.26M–$4.5M through private placements (demonstrating investor support in a challenging market).

2025

Manitoba Lung Association Grant: Support for a pilot First Nations lung cancer detection program (advancing health equity and community access).

2024 / 2025

Additional non-dilutive grant funding secured from NRC-IRAP, Mitacs, Research Manitoba, and City of Quebec, contributing to a total of over CAD $365,000 in grants during the fiscal year (as highlighted in company FY2025 achievements).

April 2024

Research Manitoba IPoC Grant + Mitacs Accelerate: Over $290,000 in combined non-dilutive funding over a two-year period. Project: “Examination of lipid nanoparticle loaded hydrogels for localized silencing of spermidine/spermine acetyl transferase-1 (SAT1) expression in tumor and enhanced radiation and chemotherapy response” (animal proof-of-concept study). Led by Dr. Donald Miller, University of Manitoba. Focuses on improving treatment response in Glioblastoma and other cancers.

November 2023

City of Quebec – Vision Entrepreneuriale Québec 2026: CAD $231,000 non-dilutive funding awarded to BioMark Diagnostic Solutions Inc. (wholly owned subsidiary) to accelerate commercialization and market development activities of its proprietary lung cancer detection assay. The funding supports business development in a clinically approved lab environment in Quebec.

February 2023

NRC-IRAP: CAD $185,900 in non-dilutive funding and advisory services.

February 2023

Global Affairs Canada (GAC) – CanExport Innovation Program: CAD $13,275.
Project: Development of a quantitative assay to measure drug metabolites for cancer treatment monitoring and relapse surveillance using BioMark’s metabolomic liquid biopsy platform.

March 2021

University of Alberta / TMIC Spark Grant: C$150,000 awarded to collaborators at the Metabolomics Innovation Centre (TMIC) to evaluate and validate BioMark’s metabolite biomarker panel for early lung cancer detection (Novel Technology Application in Cancer Prevention and Early Detection Spark Grants competition).

2019

Collaborative Health Research Projects (CHRP) Funding: Jointly supported by CIHR, NSERC, and SSHRC. BioMark served as the industrial partner on the grant.

2018

Going Global Innovation (GGI) – Canadian Trade Commissioner Service: Funding to support travel to Japan and the United States to seek partners and establish collaborative R&D agreements.

March 2015

BIAP (Business Innovation Access Program) under NRC-IRAP: Funding for “Novel Recombinant Antibodies to Assess SSAT-1 Activity as a Biomarker for the Diagnosis of Cancer” (led by Dr. Horacio Bach).

2013

NRC-IRAP Funding: Support for developing prototypes for cancer screening kits and IR system.

2013

Genome BC Funding: For “Raman Quantification of Cancer Biomarkers for Early Lung Cancer Detection” (in collaboration with Dr. Reuven Gordon and Dr. Fraser Hof, University of Victoria).

2010

NSERC Engage Grants: Six grants in collaboration with professors from University of British Columbia, University of Victoria, University of Waterloo, University of Alberta, and University of Manitoba.

2010

Mitacs: Five projects supported through the Mitacs program, with ongoing commitment to fund additional postdoctoral students.

2010

CSB (Commercialization Support for Business): Funding under the Minister of Jobs and the Economy, Government of Manitoba.

Achievements and Milestones

2025 to 2026
Advisory Team
Scientific Leadership

Broadened scientific leadership through continued advisory team growth and strategic collaborations.

2025 to 2026
Publications
9+ Peer Reviewed Publications

Over 9 peer-reviewed publications positioning BioMark as a thought leader in metabolomics and AI-based oncology diagnostics.

2025 to 2026
IP and Notice of Patent
Strengthening of IP Holdings

Ongoing patent filings and grants (including Notice of Patent Allowance in June 2026 for urine-based lung cancer screening assay).

2025 to 2026
Exclusive Selection
HANSE Trial Selection

Chosen as the exclusive partner for Germany’s largest prospective lung cancer screening trial (10,000 patients) since the NELSON trial.

2025
Award
ADRIQ Innovation Award

Awarded to BioMark and research partners from IUCPQ-UL (Institut universitaire de cardiologie et de pneumologie de Québec – Université Laval) at the 35th ADRIQ Innovation Awards Gala for the collaborative multimodal lung cancer screening project (AI-driven metabolomic blood test + clinical data + biobank from 3,000+ screened patients).

2024 to 2025
Study
7,000-Patient Lung Cancer Study

7,000+ patient study completed in Canada — one of the largest lung cancer diagnostic studies, generating robust real-world evidence.

2024 to 2025
Presenter
Presenter at International Conferences

Presentations at major international conferences including San Antonio Breast Cancer Symposium (SABCS) 2023 & 2024, USCAP, GPEN, Canadian Thoracic Society Research Forum, CARST Saskatoon, and others.

2024 to 2025
Peer Reviewed Publications

Multiple peer-reviewed publications in high-impact journals (including Cancers Journal September 2024 on NETs, Frontiers in Oncology January 2026 on machine learning models for lung cancer detection, and others in IJMS).

2023
USPTO
U.S. Patent Granted

U.S. Patent Granted (May 31, 2023) — USPTO Patent No. 11,656,229 for “Method of Detecting Lung Cancer” (liquid biopsy assay; part of a larger family of patents).

2019
ASCO Annual Meeting Poster

“Follow-up evaluation of outliers with elevated spermine-spermidine acetyltransferase-1 activity” presented.

2018
Advisory Recruitment
Expanded Capabilities

Expanded scientific, clinical, and data science capabilities by recruiting leading experts to the advisory team.

2018
Development Project
Mass Spectrometry System

Initiated development for a cost-effecive mass spectrometry system for quantification and qualification of markers, with the goal of further reducing cost per test while increasing the speed of analysis and results feedback.

2018
Strategic Alignments
Strategic Alignments and Collaboration Agreements

Biomark Diagnostics signed agreements and NDAs with distinguished laboratory, diagnostics, research, and data analytics companies in the United States, Canada, France, and Germany.

2018
Presenter
Global Oncology and Biomarker Symposiums

Biomark Diagnostics, its founder and researchers were invited to present at major global oncology and biomarker conferences and symposiums in London, Paris, Beijing, and Boston.

2018
Genome Canada's LSARP Competition

(in collaboration with TMIC — The Metabolomics Innovation Centre).

2018
Partnership
Alberta Machine Intelligence Institute (AMII)

Incorporated machine learning and artificial intelligence into lung cancer retrospective studies to improve assay performance.

2018
Trademarks and Patents (Europe & China)

BioMark continued its filings of trademarks and patents in significant key jurisdictions. New patents were filed as the company discovered additional biomarker panels.

2018
Shortlisted
CHRP Application

Submitted by Drs. Don Miller, Thomas Klonish, Ted Lakowski, Marshall Pitz, and David Wishart for a focused study on SAT1 as a biomarker for improved detection and clinical management of brain tumors.

2018
Ethics Approvals

BioMark Diagnostics received and was approved for three major ethics approvals, from which trials were commissioned for research and testing.

2018
Two Scientific Publications

BioMark Diagnostics, Rashid Ahmed Bux, and the BioMark team participated and contributed to two scientific publications related to cancer and early-stage detection.

2017
USPTO & CIPO
Multiple Patents Issued

BioMark Diagnostics was granted multiple patents for its AI and early-detection technologies by the USPTO and CIPO.

2017
Award Recipient
Going Global Award

Awarded by Global Affairs Canada to support meetings with three major Japanese companies for potential collaboration.

2013
Participant
AdvaMed

BioMark was selected for a second time to participate in AdvaMed in Washington, DC (funded by DFAIT — Department of Foreign Affairs, Trade and Development Canada).

2011
Participant
AdvaMed

BioMark was selected to participate in AdvaMed in Washington, DC (funded by DFAIT — Department of Foreign Affairs, Trade and Development Canada).

2010 to 2012
First Cohort
Canadian Technology Accelerator Program

BioMark was selected as one of the first group of Canadian companies to participate and travel to Mission Bay in Silicon Valley.

2009
Finalist
Region New Technology Awards

BioMark Diagnostics is named a finalist for this prestigious award supported by the National Research Council of Canada (NRC).

Strategic Collaborations

Pharma and Equipment

AstraZeneca Canada official logo, a BioMark Diagnostics pharmaceutical partner in early lung cancer screening and liquid biopsy research.
Pfizer Canada official logo, a BioMark Diagnostics oncology partner supporting early lung cancer detection research in Quebec.
Phytronix Technologies logo, Quebec mass-spectrometry partner of BioMark Diagnostics for high-throughput lung cancer assay development.
Roche logo - a BioMark Diagnostics partner
Sciex logo - a BioMark Diagnostics partner

Academic

University of Alberta coat of arms logo, academic partner supporting BioMark Diagnostics machine learning and metabolomics research.
Harrisburg University of Science and Technology logo, U.S. data-science partner developing machine-learning models for BioMark Diagnostics.
TMIC The Metabolomics Innovation Centre logo, national metabolomics network partner of BioMark Diagnostics.
university manitoba biomark diagnostics partner
university of british columbia biomark partner
university victoria biomark diagnostics partner
University of Maryland School of Medicine logo - a BioMark Diagnostics partner

Hospitals and Cancer Centres

Logo of the Institut universitaire de cardiologie et de pneumologie de Québec – Université Laval, BioMark’s Quebec lung cancer clinical partner.
The James at The Ohio State University Comprehensive Cancer Center logo, a U.S. oncology collaborator featured by BioMark Diagnostics.
Mount Sinai Health System logo, U.S. academic medical partner connected to BioMark Diagnostics lung cancer research.
CancerCare Manitoba and ActionCancer Manitoba logo, a provincial cancer-agency partner of BioMark Diagnostics.
Hôpital St-Boniface Hospital Research logo, Winnipeg clinical and translational research partner of BioMark Diagnostics.
Hospices Civils de Lyon HCL logo, French university hospital partner supplying lung cancer screening samples to BioMark Diagnostics.
Medizinische Hochschule Hannover MHH logo, German academic medical partner of BioMark Diagnostics on the HANSE lung cancer screening trial.

Healthcare, Government, and Foundation Partners (Canada)

MEDTEQ+ L’innovation pour la santé logo, Quebec medical-technology consortium supporting BioMark Diagnostics.
CQDM SynergiQc logo, Quebec biopharmaceutical research consortium that funded BioMark’s lung cancer screening collaboration.
CIHR-IRSC Institute of Cancer Research logo, Canadian Institutes of Health Research institute that has funded BioMark-linked lung cancer work.
Research Manitoba logo, provincial health-research agency supporting BioMark-linked innovation and proof-of-concept work.
Fondation Brain Canada Foundation logo, national research foundation that has co-funded BioMark-linked cancer assay development.
Canadian Cancer Society yellow daffodil logo, national cancer charity that has funded and aligned with BioMark Diagnostics’ early detection work.
RSRQ Réseau de recherche en santé respiratoire du Québec logo, Quebec respiratory research network partner of BioMark Diagnostics.
CNETS Canadian Neuroendocrine Tumour Society logo with zebra mark, patient-research partner connected to BioMark NET studies.
BIOTECanada logo, Canada’s national biotechnology industry association of which BioMark Diagnostics is part of the life-sciences community.
LE CAMP Incubateur Accélérateur logo, Quebec City innovation hub listed as a BioMark Diagnostics ecosystem partner.
Manitoba Lung Association BREATHE logo, provincial lung-health charity partnering with BioMark Diagnostics on early detection outreach.
MCF My Charity Fund logo, Canadian charitable-giving partner listed in BioMark Diagnostics’ foundation network.
Lung Cancer Canada - logo - a BioMark Diagnostics partner
Ville de Quebec - logo - a BioMark Diagnostics partner

BioMark is actively expanding its network of strategic collaborations with leading researchers, institutions, and organizations dedicated to transforming cancer diagnostics. If your work aligns with advancing metabolomics-based liquid biopsy technologies — whether through clinical sample access, analytical method development, or co-development partnerships — we would welcome the opportunity to connect. Please email [email protected] to explore how we can work together.

Career Opportunities

Thank you for your interest in BioMark Diagnostics. We are continuously driven by innovation and a shared passion for transforming healthcare through advanced diagnostics. While we do not have any open job listings at this time, we are always eager to connect with exceptionally talented individuals. If your expertise lies in Artificial Intelligence, Machine Learning, Healthcare Science, Cancer Research, or Metabolic Sciences, we invite you to share your resume and a brief introduction for future consideration. Please feel free to send your inquiries to our team via [email protected]

If you have been contacted by someone claiming to represent our company regarding a job opportunity, please exercise caution. Do not provide any personal, confidential, or financial information until you have verified the recruiter’s identity. To confirm whether a recruiter is genuinely affiliated with us, please contact us directly at [email protected].

If you believe you have been targeted by a fraudulent recruiter, we encourage you to report the incident to your local police department.

Current Job Listings

No openings at this time

Sign up for the latest BioMark news